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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	terbutaline
Molecular formula	C12H19NO3
IUPAC name	5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diol
Molecular weight	225.288
Hydrogen bond acceptor	4
Hydrogen bond donor	4
XlogP	0.9
Synonyms	5-[2-(tert-butylamino)-1-oxidanyl-ethyl]benzene-1,3-diol SCHEMBL4391 AKOS015889885 SR-01000000174 Benzyl alcohol, alpha-((t-butylamino)methyl)-3,5-dihydroxy- Terbutaline sulfate Brethine (TN) Terbutalinum [INN-Latin] BRN 2370513 CTK8E4128 FT-0654976 KBio2_004078 1,3-Benzenediol, 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)- Lopac0_001126 23031-32-5 (Sulfate) Oprea1_823972 Prestwick0_000391 A816514 Spectrum2_001327 Asthmasian Terbutalina BRD-A50157456-065-12-3 Terbutaline,(+/-) Bricanyl (Salt/Mix) XWTYSIMOBUGWOL-UHFFFAOYSA-N C07129 IDI1_000078 KBioGR_001539 1,3-Benzenediol, 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-, (+-)- NCGC00016010-03 5-(2-((1,1-DIMETHYLETHYL)AMINO)-1-HYDROXYETHYL)-1,3-BENZENEDIOL 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diol Prestwick3_000391 AC1L1KA2 Spectrum5_001262 BDBM25770 Terbutaline (INN) Brethaire (TN) Terbutalino [INN-Spanish] Bricaril DTXSID7021310 KBio1_000078 KWD-2019 2-t-Butylamino-1-(3,5-dihydroxyphenyl)ethanol NCGC00089821-02 PDSP1_000158 5-{2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl}benzene-1,3-diol SPBio_001453 alpha-[(tert-butylamino)methyl]-3,5-dihydroxybenzenemethanol SR-01000000174-2 BPBio1_000663 Terbutaline sulfate (Salt/Mix) Brican TR-036208 BSPBio_000601 D08570 GTPL560 KBio2_006646 1,3-Benzenediol, 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)- (9CI) LS-29961 Prestwick1_000391 AB00053548 Spectrum3_000593 Asthmasian (TN) Terbutalina [DCIT] Brethaire Terbutalini sulfas Bricanyl (TN) CCG-205201 DB00871 J-014950 (+-)-5-(2-((1,1-Dimethylethyl)amino)-1-hydroxyethyl)-1,3-benzenediol KBioSS_001510 1,3-Benzenediol, 5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]- NCGC00016010-04 5-(2-(tert-Butylamino)-1-hydroxyethyl)benzene-1,3-diol 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diol, 5 SBI-0051094.P004 ACM23031256 Spectrum_001030 Benzyl alcohol, .alpha.-((t-butylamino)methyl)-3,5-dihydroxy- Terbutaline (sulfate de) Brethine Terbutalinum Bricyn CHEMBL1760 EINECS 245-385-8 KBio2_001510 031T256 L000594 23031-25-6 NINDS_000078 PDSP2_000157 SPBio_002522 API0005740 Terbutalin BRD-A50157456-065-02-4 Terbutaline [INN:BAN] Bricanyl VA11844 BSPBio_002066 D0M8RC I01-3464 KBio3_001566 1,3-Benzenediol, 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-(9CI) LS-7713 46719-29-3 5-[2-(tert-Butylamino)-1-hydroxyethyl]-1,3-benzenediol # Prestwick2_000391 AB00053548_15 Spectrum4_000870 AX8152612 Brethaire (Salt/Mix) Terbutalino Bricar CHEBI:9449 DivK1c_000078 KB-243251 (+-)-Terbutaline KWD 2019 1-(3',5'-dihydroxyphenyl)-2-(t-butylamino)-ethanol NCGC00016010-06 [ Show all ]
Inchi Key	XWTYSIMOBUGWOL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H19NO3/c1-12(2,3)13-7-11(16)8-4-9(14)6-10(15)5-8/h4-6,11,13-16H,7H2,1-3H3
PubChem CID	5403
ChEMBL	CHEMBL1760
IUPHAR	560
BindingDB	25770
DrugBank	DB00871
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
402830	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
402828	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
402829	Beta-2 adrenergic receptor	Q28044	ADRB2	Bos taurus (Bovine)	418
402827	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408

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