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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1270383
Molecular formula	C28H30N2O2
IUPAC name	(1R,14S,15R)-25-(cyclobutylmethyl)-4,25-diazahexacyclo[13.7.3.01,14.03,12.05,10.017,22]pentacosa-3,5,7,9,11,17(22),18,20-octaene-14,20-diol
Molecular weight	426.56
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.7
Synonyms	BDBM224027 BDBM50329098
Inchi Key	XTQJMKKUNXFEFW-JCYYIGJDSA-N
Inchi ID	InChI=1S/C28H30N2O2/c31-22-9-8-19-13-26-28(32)15-21-12-20-6-1-2-7-24(20)29-25(21)16-27(28,23(19)14-22)10-11-30(26)17-18-4-3-5-18/h1-2,6-9,12,14,18,26,31-32H,3-5,10-11,13,15-17H2/t26-,27-,28-/m1/s1
PubChem CID	52943376
ChEMBL	CHEMBL1270383
IUPHAR	N/A
BindingDB	224027, 50329098
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
400623	Delta-type opioid receptor	P32300	Oprd1	Mus musculus (Mouse)	372
400625	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
569763	Mas-related G-protein coupled receptor member X2	Q96LB1	MRGPRX2	Homo sapiens (Human)	330
400624	Mu-type opioid receptor	P42866	Oprm1	Mus musculus (Mouse)	398

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