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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	Dirigestran
Molecular formula	C55H75N17O13
IUPAC name	N-[1-[[1-[[1-[[1-[[2-[[1-[[1-[2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Molecular weight	1182.31
Hydrogen bond acceptor	15
Hydrogen bond donor	16
XlogP	-2.4
Synonyms	Relisorm Dirigestran Spofa Synthetic LH-FSH-RH Glycinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-L-arginyl-L-prolyl- XLXSAKCOAKORKW-UHFFFAOYSA-N Gonadorelin [INN:BAN] Gonadotropin-releasing hormone I LH-FSH Releasing Hormone LHRH, human Luteinizing hormone-releasing factor (human) Lutrepulse KIT N-[2-[[2-[[2-[[2-[[2-[[1-[[1-[2-[(2-amino-2-oxo-ethyl)carbamoyl]pyrrolidine-1-carbonyl]-4-guanidino-butyl]carbamoyl]-3-methyl-butyl]amino]-2-oxo-ethyl]amino]-1-[(4-hydroxyphenyl)methyl]-2-oxo-ethyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-1-(1H-indol-3 AY-24031 CHEMBL1981292 Synthetic Gn-RH Fertagyl Synthetic LH-releasing hormone/FSH-releasing hormone Gonadoliberin I Gonadoreline Hypocrine LH-RH Lutal Luteinizing hormone-releasing factor (sheep) Mammalian LH-RH 6918-09-8 Ovine LH-RH pyroGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 DB00644 Synthetic gonadotropin-releasing hormone FSH-Releasing Hormone Synthetic LH-RH/FSH-RH Gonadorelin (INN) Gonadotropin, luteinizing hormone-releasing hormone, synthetic L000690 LHFSHRH Luteinizing hormone releasing hormone Luteinizing hormone-releasing hormone (swin) N-[1-[[1-[[1-[[1-[[2-[[1-[[1-[2-[(2-azanyl-2-oxidanylidene-ethyl)carbamoyl]pyrrolidin-1-yl]-5-[bis(azanyl)methylideneamino]-1-oxidanylidene-pentan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]amino]-2-oxidanylidene-ethyl]amino]-3-(4-hydroxyphenyl)-1-o AC1L1VXF C07607 Relisorm l EINECS 251-553-1 Synthetic LH-releasing factor Gn-RH Gonadorelina HOE 471 LH-Releasing factor (pig) LS-174422 Luteinizing hormone-releasing factor (pig) Mammalian GnRH NCGC00182043-01 D04ODH Synthetic gonadoliberin Fertagyl (TN) Synthetic LH-RF Gonadoliberin, Luliberin Gonadorelinum I06-0360 LH-RH (swine) Lutamin Luteinizing hormone-releasing factor (swine) MammalianGnRH 9034-40-6 Porchine LH-RH Relefact Synthetic LH-FSH releasing hormone FT-0628048 Synthetic LRF Gonadorelin decapeptide Gonadotropin-releasing hormone LFRH LHRH Luteinizing hormone releasing hormone human Lutrefact N-[1-[[1-[[1-[[1-[[2-[[1-[[1-[2-[[(2-amino-2-oxoethyl)amino]-oxomethyl]-1-pyrrolidinyl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropa AN-7551 C55H75N17O13 Synthetic decapeptide FSH/LH-RH Factrel Synthetic LH-releasing hormone GnRH-I Gonadorelina [INN-Spanish] Human LH-RH LH-Releasing hormone (porcine) Luforan Luteinizing hormone-releasing factor (rat) Mammalian gonadotropin-releasing hormone Ovine gonadotropin-releasing hormone Porcine LH-releasing factor Synthetic gonadotropic hormone-releasing hormone Follicle-stimulating hormone-releasing factor (pig) Synthetic LH-RH GONADORELIN Gonadorelinum [INN-Latin] Kryptocur LHFSH Releasing Hormone LUTEINIZING HORMONE Luteinizing hormone-releasing hormone MT-BT A821811 [ Show all ]
Inchi Key	XLXSAKCOAKORKW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C55H75N17O13/c1-29(2)19-38(49(80)67-37(9-5-17-60-55(57)58)54(85)72-18-6-10-43(72)53(84)62-25-44(56)75)66-46(77)26-63-47(78)39(20-30-11-13-33(74)14-12-30)68-52(83)42(27-73)71-50(81)40(21-31-23-61-35-8-4-3-7-34(31)35)69-51(82)41(22-32-24-59-28-64-32)70-48(79)36-15-16-45(76)65-36/h3-4,7-8,11-14,23-24,28-29,36-43,61,73-74H,5-6,9-10,15-22,25-27H2,1-2H3,(H2,56,75)(H,59,64)(H,62,84)(H,63,78)(H,65,76)(H,66,77)(H,67,80)(H,68,83)(H,69,82)(H,70,79)(H,71,81)(H4,57,58,60)
PubChem CID	36523
ChEMBL	N/A
IUPHAR	N/A
BindingDB	N/A
DrugBank	DB00644
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
395310	Gonadotropin-releasing hormone receptor	P30968	GNRHR	Homo sapiens (Human)	328
395309	Putative gonadotropin-releasing hormone II receptor	Q96P88	GNRHR2	Homo sapiens (Human)	292

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