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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3355945
Molecular formula	C25H31FN2S
IUPAC name	2-ethyl-3-[1-[3-(4-fluorophenyl)sulfanylpropyl]piperidin-4-yl]-6-methyl-1H-indole
Molecular weight	410.595
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	6.5
Synonyms	BDBM50041186
Inchi Key	TVSACSZJCZUBIY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H31FN2S/c1-3-23-25(22-10-5-18(2)17-24(22)27-23)19-11-14-28(15-12-19)13-4-16-29-21-8-6-20(26)7-9-21/h5-10,17,19,27H,3-4,11-16H2,1-2H3
PubChem CID	118721195
ChEMBL	CHEMBL3355945
IUPHAR	N/A
BindingDB	50041186
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
454750	C-C chemokine receptor type 3	P51677	CCR3	Homo sapiens (Human)	355
454751	C-C chemokine receptor type 3	O54814	Ccr3	Rattus norvegicus (Rat)	359
454749	Probable C-C chemokine receptor type 3	P51678	Ccr3	Mus musculus (Mouse)	359

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