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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3355946
Molecular formula	C24H29FN2OS
IUPAC name	2-ethyl-3-[1-[3-(4-fluorophenyl)sulfanylpropyl]piperidin-4-yl]-1H-indol-6-ol
Molecular weight	412.567
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	5.8
Synonyms	BDBM50041187
Inchi Key	RUBACXIFRPVRKI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H29FN2OS/c1-2-22-24(21-9-6-19(28)16-23(21)26-22)17-10-13-27(14-11-17)12-3-15-29-20-7-4-18(25)5-8-20/h4-9,16-17,26,28H,2-3,10-15H2,1H3
PubChem CID	118721196
ChEMBL	CHEMBL3355946
IUPHAR	N/A
BindingDB	50041187
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
453780	C-C chemokine receptor type 3	O54814	Ccr3	Rattus norvegicus (Rat)	359
453781	C-C chemokine receptor type 3	P51677	CCR3	Homo sapiens (Human)	355
453779	Probable C-C chemokine receptor type 3	P51678	Ccr3	Mus musculus (Mouse)	359

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