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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3355954
Molecular formula	C31H32F2N6S
IUPAC name	2-ethyl-6-fluoro-3-[1-[3-(4-fluorophenyl)sulfanylpropyl]piperidin-4-yl]-1-[4-(2H-tetrazol-5-yl)phenyl]indole
Molecular weight	558.696
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	7.0
Synonyms	BDBM50041193
Inchi Key	QTAMIHYZGWVETD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H32F2N6S/c1-2-28-30(21-14-17-38(18-15-21)16-3-19-40-26-11-6-23(32)7-12-26)27-13-8-24(33)20-29(27)39(28)25-9-4-22(5-10-25)31-34-36-37-35-31/h4-13,20-21H,2-3,14-19H2,1H3,(H,34,35,36,37)
PubChem CID	118721200
ChEMBL	CHEMBL3355954
IUPHAR	N/A
BindingDB	50041193
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
452975	C-C chemokine receptor type 3	O54814	Ccr3	Rattus norvegicus (Rat)	359
452976	C-C chemokine receptor type 3	P51677	CCR3	Homo sapiens (Human)	355
452974	Probable C-C chemokine receptor type 3	P51678	Ccr3	Mus musculus (Mouse)	359

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