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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL302411
Molecular formula	C17H18N2O4
IUPAC name	(2R,4R)-4-amino-1-(naphthalen-1-ylmethyl)pyrrolidine-2,4-dicarboxylic acid
Molecular weight	314.341
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	-3.3
Synonyms	BDBM50071159 SCHEMBL8973459 (2R,4R)-4-Amino-1-naphthalen-1-ylmethyl-pyrrolidine-2,4-dicarboxylic acid
Inchi Key	QAHGNZYFTSTHIG-RHSMWYFYSA-N
Inchi ID	InChI=1S/C17H18N2O4/c18-17(16(22)23)8-14(15(20)21)19(10-17)9-12-6-3-5-11-4-1-2-7-13(11)12/h1-7,14H,8-10,18H2,(H,20,21)(H,22,23)/t14-,17-/m1/s1
PubChem CID	10358265
ChEMBL	CHEMBL302411
IUPHAR	N/A
BindingDB	50071159
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
273367	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
273372	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
273368	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
273370	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
273371	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
273369	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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