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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3618201
Molecular formula	C31H26F2N2O6
IUPAC name	4-[3-(4-fluorophenoxy)-5-[[4-(4-fluorophenyl)-4-hydroxypiperidine-1-carbonyl]amino]phenoxy]benzoic acid
Molecular weight	560.554
Hydrogen bond acceptor	8
Hydrogen bond donor	3
XlogP	5.0
Synonyms	BDBM149705 SCHEMBL14839451 US8975409, Example 9(3)
Inchi Key	PZFBUIYFAFMDBM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H26F2N2O6/c32-22-5-3-21(4-6-22)31(39)13-15-35(16-14-31)30(38)34-24-17-27(40-25-9-1-20(2-10-25)29(36)37)19-28(18-24)41-26-11-7-23(33)8-12-26/h1-12,17-19,39H,13-16H2,(H,34,38)(H,36,37)
PubChem CID	71547555
ChEMBL	CHEMBL3618201
IUPHAR	N/A
BindingDB	149705
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
496631	Sphingosine 1-phosphate receptor 1	P21453	S1PR1	Homo sapiens (Human)	382
272620	Sphingosine 1-phosphate receptor 2	O95136	S1PR2	Homo sapiens (Human)	353
461573	Sphingosine 1-phosphate receptor 2	P47752	S1pr2	Rattus norvegicus (Rat)	352
496633	Sphingosine 1-phosphate receptor 3	Q99500	S1PR3	Homo sapiens (Human)	378
496632	Sphingosine 1-phosphate receptor 4	O95977	S1PR4	Homo sapiens (Human)	384
496630	Sphingosine 1-phosphate receptor 5	Q9H228	S1PR5	Homo sapiens (Human)	398

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