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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1099114
Molecular formula	C23H15FN2
IUPAC name	2-(4-fluorophenyl)-5-(2-methylquinolin-7-yl)benzonitrile
Molecular weight	338.385
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	5.7
Synonyms	BDBM50317850 5-(2-Methylquinolin-7-yl)-2-(4-fluorophenyl)benzonitrile
Inchi Key	PQZMWEWZHYNTAZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H15FN2/c1-15-2-3-17-4-5-19(13-23(17)26-15)18-8-11-22(20(12-18)14-25)16-6-9-21(24)10-7-16/h2-13H,1H3
PubChem CID	46888046
ChEMBL	CHEMBL1099114
IUPHAR	N/A
BindingDB	50317850
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
266668	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
266666	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
266664	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
266663	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
266665	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
266667	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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