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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL523716
Molecular formula	C17H19FN6O
IUPAC name	2-[4-(7-fluoropyrrolo[1,2-a]quinoxalin-4-yl)piperazin-1-yl]-N'-hydroxyethanimidamide
Molecular weight	342.378
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	2.4
Synonyms	BDBM50258431 [4-(7-Fluoropyrrolo[1,2-a]quinoxalin-4-yl)piperazin-1-yl]hydroxyacetamidine
Inchi Key	OHKKNUFVKFSRIU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H19FN6O/c18-12-3-4-14-13(10-12)20-17(15-2-1-5-24(14)15)23-8-6-22(7-9-23)11-16(19)21-25/h1-5,10,25H,6-9,11H2,(H2,19,21)
PubChem CID	44157734
ChEMBL	CHEMBL523716
IUPHAR	N/A
BindingDB	50258431
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
241415	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
241419	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
241418	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
241416	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
241417	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
241414	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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