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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1819623
Molecular formula	C25H22ClFN2O5
IUPAC name	2-[3-[[2-chloro-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]-4-fluorophenyl]acetic acid
Molecular weight	484.908
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	4.5
Synonyms	BDBM50351484 SCHEMBL2189227
Inchi Key	NYJIUFYVDCEUIV-KRWDZBQOSA-N
Inchi ID	InChI=1S/C25H22ClFN2O5/c1-29-13-17(34-23-5-3-2-4-22(23)29)14-33-16-7-8-18(19(26)12-16)25(32)28-21-10-15(11-24(30)31)6-9-20(21)27/h2-10,12,17H,11,13-14H2,1H3,(H,28,32)(H,30,31)/t17-/m0/s1
PubChem CID	56672020
ChEMBL	CHEMBL1819623
IUPHAR	N/A
BindingDB	50351484
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
235043	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
235041	Prostaglandin D2 receptor	P70263	Ptgdr	Mus musculus (Mouse)	357
235044	Prostaglandin E2 receptor EP1 subtype	P35375	Ptger1	Mus musculus (Mouse)	405
235040	Prostaglandin E2 receptor EP2 subtype	Q62053	Ptger2	Mus musculus (Mouse)	362
235037	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
235038	Prostaglandin E2 receptor EP4 subtype	P32240	Ptger4	Mus musculus (Mouse)	513
235042	Prostaglandin F2-alpha receptor	P43117	Ptgfr	Mus musculus (Mouse)	366
235039	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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