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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	betaxolol
Molecular formula	C18H29NO3
IUPAC name	1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
Molecular weight	307.434
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.8
Synonyms	DSSTox_RID_76685 K005 1-(4-(2-(Cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol Lopac0_000193 1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-(propan-2-ylamino)propan-2-ol NCGC00015159-09 A834454 Prestwick3_000382 API0024704 SPBio_002484 Betaxolol (TN) Betoptic (TN) C06849 CS-2452 GTPL549 Kerlone (TN) 1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol MRF-0000336 NCGC00024863-04 AC1L1DIZ SC-23071 BDBM50405521 Tox21_110091 Betaxolol [INN:BAN] BPBio1_000621 CC-24642 D07526 DSSTox_CID_2674 HY-B0381 (.+/-.)-1-[p-[2-(Cyclopropylmethoxy)ethyl]phenoxy]-3-(isopropylamino)-2-propanol L000125 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)-2-propanol NCGC00015159-06 63659-19-8 (hydrochloride) Prestwick1_000382 ALO-1401-02 SL-75212 Betaxolol (Betoptic) Betazolol BSPBio_000563 DTXSID2022674 KERLEDEX 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-(isopropylamino)propan-2-ol LS-122005 2-Propanol, 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)- NCGC00015159-11 AB2000495 Q-200713 AS-14125 SW196917-5 Betaxolol HCL Betoptic S C18H29NO3 CTK8F0838 HMS2089I07 KM0772 1-[(4-{2-[(cyclopropylmethyl)oxy]ethyl}phenyl)oxy]-3-[(1-methylethyl)amino]propan-2-ol NCGC00015159-04 NWIUTZDMDHAVTP-UHFFFAOYSA-N AK546815 SCHEMBL23530 beta-Xolol Tox21_110091_1 Betaxololum BRD-A02759312-003-03-9 CCG-204288 DSSTox_GSID_22674 I14-16995 (3-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-2-hydroxypropyl)(propan-2-yl)amine Lokren (TN) 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol NCGC00015159-08 659X187 Prestwick2_000382 AN-1136 SL-75212-10 Betaxolol (INN) Betoptic C-19113 CHEMBL423 FT-0601531 Kerlone 1-(4-[2-(Cyclopropylmethoxy)ethyl]phenoxy)-3-(isopropylamino)-2-propanol # MolPort-003-845-027 2-Propanol,1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]- NCGC00024863-03 AC-1115 s2091 BC227945 TC-030604 Betaxolol S Betoptic S (TN) CAS-63659-18-7 D03ROX HMS3655P17 (+/-)-1-[p-[2-(Cyclopropylmethoxy)ethyl]phenoxy]-3-(isopropylamino)-2-propanol KS-00001F72 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(isopropylamino)propan-2-ol NCGC00015159-05 63659-18-7 Prestwick0_000382 AKOS015841671 SL 75212 Betaxololum [INN-Latin] BRD-A02759312-003-11-2 CHEBI:3082 DB00195 [ Show all ]
Inchi Key	NWIUTZDMDHAVTP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H29NO3/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3
PubChem CID	2369
ChEMBL	CHEMBL423
IUPHAR	549
BindingDB	50405521
DrugBank	DB00195
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
233754	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
233755	Beta-1 adrenergic receptor	P18090	Adrb1	Rattus norvegicus (Rat)	466
233753	Beta-2 adrenergic receptor	Q8K4Z4	Adrb2	Cavia porcellus (Guinea pig)	418
233756	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
233757	Beta-2 adrenergic receptor	Q28044	ADRB2	Bos taurus (Bovine)	418

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