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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL101138
Molecular formula	C21H26N4O2S
IUPAC name	2-[5-(5-benzyl-1,1-dioxo-1,2,5-thiadiazolidin-2-yl)-1H-indol-3-yl]-N,N-dimethylethanamine
Molecular weight	398.525
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.7
Synonyms	SCHEMBL8806725 2-[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]-5-benzyl-1,2,5-thiadiazolidine 1,1-dioxide BDBM50422022
Inchi Key	NFLDDZPDKNUJJZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H26N4O2S/c1-23(2)11-10-18-15-22-21-9-8-19(14-20(18)21)25-13-12-24(28(25,26)27)16-17-6-4-3-5-7-17/h3-9,14-15,22H,10-13,16H2,1-2H3
PubChem CID	10340828
ChEMBL	CHEMBL101138
IUPHAR	N/A
BindingDB	50422022
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
222014	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
222015	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
222016	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357

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