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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL439775
Molecular formula	C22H23NO5
IUPAC name	(1S,2S,3S)-2-[1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-ethylcyclopropane-1-carboxylic acid
Molecular weight	381.428
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	0.7
Synonyms	(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-3-ethyl-cyclopropanecarboxylic acid BDBM50072172
Inchi Key	NBAKIHCDPVZWRB-LFNZXSRPSA-N
Inchi ID	InChI=1S/C22H23NO5/c1-2-12-18(20(24)25)19(12)22(23,21(26)27)11-15-13-7-3-5-9-16(13)28-17-10-6-4-8-14(15)17/h3-10,12,15,18-19H,2,11,23H2,1H3,(H,24,25)(H,26,27)/t12-,18+,19+,22?/m1/s1
PubChem CID	44329042
ChEMBL	CHEMBL439775
IUPHAR	N/A
BindingDB	50072172
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
218949	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
218944	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
218950	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
218946	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
218945	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
218947	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
218948	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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