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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3355952
Molecular formula	C26H30F2N2O2S
IUPAC name	2-[2-ethyl-6-fluoro-3-[1-[3-(4-fluorophenyl)sulfanylpropyl]piperidin-4-yl]indol-1-yl]acetic acid
Molecular weight	472.595
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.6
Synonyms	BDBM50041191 SCHEMBL1107157
Inchi Key	MPXYNWUUGMMVRW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H30F2N2O2S/c1-2-23-26(22-9-6-20(28)16-24(22)30(23)17-25(31)32)18-10-13-29(14-11-18)12-3-15-33-21-7-4-19(27)5-8-21/h4-9,16,18H,2-3,10-15,17H2,1H3,(H,31,32)
PubChem CID	24937215
ChEMBL	CHEMBL3355952
IUPHAR	N/A
BindingDB	50041191
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
450005	C-C chemokine receptor type 3	O54814	Ccr3	Rattus norvegicus (Rat)	359
450006	C-C chemokine receptor type 3	P51677	CCR3	Homo sapiens (Human)	355
450004	Probable C-C chemokine receptor type 3	P51678	Ccr3	Mus musculus (Mouse)	359

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