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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL133939
Molecular formula	C15H20N2O
IUPAC name	5-methoxy-3-[[(2S)-1-methylpyrrolidin-2-yl]methyl]-1H-indole
Molecular weight	244.338
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	2.9
Synonyms	5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indole ZINC5452 BDBM50081702 MKEGUJPBCIXABO-LBPRGKRZSA-N 5-Methoxy-3-[[(2S)-1-methylpyrrolidin-2-yl]methyl]-1H-indole (S)-5-Methoxy-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole SCHEMBL8790464 [ Show all ]
Inchi Key	MKEGUJPBCIXABO-LBPRGKRZSA-N
Inchi ID	InChI=1S/C15H20N2O/c1-17-7-3-4-12(17)8-11-10-16-15-6-5-13(18-2)9-14(11)15/h5-6,9-10,12,16H,3-4,7-8H2,1-2H3/t12-/m0/s1
PubChem CID	10105889
ChEMBL	CHEMBL133939
IUPHAR	N/A
BindingDB	50081702
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
207460	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
207463	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
207462	5-hydroxytryptamine receptor 1D	Q60484	HTR1D	Cavia porcellus (Guinea pig)	376
207464	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
207461	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460

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