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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL297150
Molecular formula	C6H11N3O4
IUPAC name	(2R,4R)-1,4-diaminopyrrolidine-2,4-dicarboxylic acid
Molecular weight	189.171
Hydrogen bond acceptor	7
Hydrogen bond donor	4
XlogP	-6.2
Synonyms	(2R,4R)-1,4-Diamino-pyrrolidine-2,4-dicarboxylic acid BDBM50078596 4-Amino-2,4-dicarboxy-pyrrolidin-1-yl-ammonium(1-Amino-APDC)
Inchi Key	MJUZIVFENBZUFH-AWFVSMACSA-N
Inchi ID	InChI=1S/C6H11N3O4/c7-6(5(12)13)1-3(4(10)11)9(8)2-6/h3H,1-2,7-8H2,(H,10,11)(H,12,13)/t3-,6-/m1/s1
PubChem CID	10330132
ChEMBL	CHEMBL297150
IUPHAR	N/A
BindingDB	50078596
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
207195	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
207194	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
207196	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
207197	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
207198	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
207199	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
207200	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877

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