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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1819612
Molecular formula	C27H28N2O5
IUPAC name	2-[3-methyl-5-[[2-methyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]acetic acid
Molecular weight	460.53
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	4.5
Synonyms	BDBM50351482 SCHEMBL2192760
Inchi Key	LYNRZWODOXOKCD-QFIPXVFZSA-N
Inchi ID	InChI=1S/C27H28N2O5/c1-17-10-19(14-26(30)31)13-20(11-17)28-27(32)23-9-8-21(12-18(23)2)33-16-22-15-29(3)24-6-4-5-7-25(24)34-22/h4-13,22H,14-16H2,1-3H3,(H,28,32)(H,30,31)/t22-/m0/s1
PubChem CID	56672019
ChEMBL	CHEMBL1819612
IUPHAR	N/A
BindingDB	50351482
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
199497	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
199501	Prostaglandin D2 receptor	P70263	Ptgdr	Mus musculus (Mouse)	357
199502	Prostaglandin E2 receptor EP1 subtype	P35375	Ptger1	Mus musculus (Mouse)	405
199500	Prostaglandin E2 receptor EP2 subtype	Q62053	Ptger2	Mus musculus (Mouse)	362
199499	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
199503	Prostaglandin E2 receptor EP4 subtype	P32240	Ptger4	Mus musculus (Mouse)	513
199496	Prostaglandin F2-alpha receptor	P43117	Ptgfr	Mus musculus (Mouse)	366
199498	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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