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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL606676
Molecular formula	C19H25N5
IUPAC name	9-phenyl-4-piperazin-1-yl-6,7,8,9-tetrahydro-5H-cyclohepta[d]pyrimidin-2-amine
Molecular weight	323.444
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.9
Synonyms	9-phenyl-4-(piperazin-1-yl)-5H,6H,7H,8H,9H-cyclohepta[d]pyrimidin-2-amine CHEMBL492231 2,4-diamino-5,6-disubstituted pyrimidine, 14 BDBM26400
Inchi Key	LTSQOGQDXSXTPV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H25N5/c20-19-22-17-15(14-6-2-1-3-7-14)8-4-5-9-16(17)18(23-19)24-12-10-21-11-13-24/h1-3,6-7,15,21H,4-5,8-13H2,(H2,20,22,23)
PubChem CID	25129169
ChEMBL	CHEMBL492231
IUPHAR	N/A
BindingDB	26400
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
196196	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445
196197	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
196193	Histamine H4 receptor	Q91ZY1	Hrh4	Rattus norvegicus (Rat)	391
196194	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390
196195	Histamine H4 receptor	Q91ZY2	Hrh4	Mus musculus (Mouse)	391

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