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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	HYDROCODONE
Molecular formula	C18H21NO3
IUPAC name	(4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
Molecular weight	299.37
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	2.2
Synonyms	125-29-1 Morphinan-6-one, 4,5-epoxy-3-methoxy-17-methyl-, (5alpha)- (9CI) 4,5alpha-Epoxy-3-methoxy-17-methylmorphinan-6-one NCGC00159317-02 9007-52-7 opioid1 CHEMBL1457 ZINC1280665 DEA No. 9193 GTPL7081 Hydrocodon Hydrocodone prodrug (Bio-MD/immediate release, pain), PharmacoFore Hydrocone KP-201 hydrocodone prodrug Lortab (TN) 3-methoxy-17-methyl-4,5alpha-epoxymorphinan-6-one Morphinan-6-one, 4,5alpha-epoxy-3-methoxy-17-methyl- (8CI) Norgan (TN) Bekadid SCHEMBL2987 D08045 Dicodid (TN) HSDB 3097 Hydrocodone 0.1 mg/ml in Methanol Hydrocodone prodrug (oral, pain), KemPharm Hydrovo (TN) (-)-Dihydrocodeinone Morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl- 4,5.alpha.-Epoxy-3-methoxy-17-methylmorphinan-6-one Morphinan-6-one,5.alpha.-epoxy-3-methoxy-17-methyl- 6YKS4Y3WQ7 NSC-19044 CHEBI:5779 UNII-6YKS4Y3WQ7 Duodin (TN) Hycomine (TN) Hydrocodone polistirex [USAN] Hydrocodonum [INN-Latin] Kolikodol (TN) (5alpha)-17-methyl-3-(methyloxy)-4,5-epoxymorphinan-6-one 1469752-80-4 Morphinan-6-one, 4,5-epoxy-3-methoxy-17-methyl-, (5alpha)-(9CI) 4-27-00-03580 (Beilstein Handbook Reference) NCGC00159317-03 Anexsia (TN) Orthoxycol (TN) Codeinone, dihydro- Zohydro DICO hidrocodona Hydrocodone prodrug (Bio-MD/MPAR/oral, pain), PharmacoFore Hydroconum LLPOLZWFYMWNKH-CMKMFDCUSA-N LS-92156 34195-34-1 (tartrate (1:1), hydrate (2:5)) Morphinan-6-one, 4,5alpha-epoxy-3-methoxy-17-methyl-(8CI) 50678-79-0 Novahistex (TN) BRN 0094193 Symtan (TN) D0C2DS Dihydrocodeinone Hycet (TN) Hydrocodone 1.0 mg/ml in Methanol Hydrocodone [INN:BAN] Idrocodone (1S,5R,13R,17R)-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0;{1,13}.0;{5,17}.0;{7,18}]octadeca-7(18),8,10-trien-14-one Morphinan-6-one, 4,5-epoxy-3-methoxy-17-methyl-, (5alpha)- 4,5alpha-epoxy-3-methoxy-17-methyl-morphinan-6-one Multacodin NSC19044 WLN: T B6566 B6/CO 4ABBC R BX FV HO PN GHT&&TTJ JO1 P1 DB00956 EINECS 204-733-9 Hydrocodeinonebitartrate Hydrocodone prodrug (Bio-MD, pain), PharmacoFore Hydrocon KP-201 1037-91-8 17-methyl-4,5alpha-epoxy-3-methoxymorphinan-6-one Morphinan-6-one, 4,5alpha-epoxy-3-methoxy-17-methyl- 4aH-8,5-bcd]furan-5-(6H)-one, 7,7a,8,9-tetrahydro-3-methoxy-12-methyl- Norco (TN) BDBM50386689 PF-06 program Codinovo Dicodid Hidrocodona [INN-Spanish] Hydrocodone (INN) Hydrocodone prodrug (Bio-MD/MPAR/oral/immediate release, pain), PharmacoFore Hydrokon (TN) Lorcet (TN) Mercodinone (TN) 4,5-alpha-Epoxy-3-methoxy-17-methylmorphinan-6-one Morphinan-6-one,5-epoxy-3-methoxy-17-methyl-, (5.alpha.)- 6-Oxo-3-methoxy-N-methyl-4,5-epoxymorphinan NSC 19044 C08024 Synkonin (TN) D0X5KF DTXSID8023131 Hycodan (TN) Hydrocodone polistirex Hydrocodonum Idrocodone [DCIT] (4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one [ Show all ]
Inchi Key	LLPOLZWFYMWNKH-CMKMFDCUSA-N
Inchi ID	InChI=1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3,6,11-12,17H,4-5,7-9H2,1-2H3/t11-,12+,17-,18-/m0/s1
PubChem CID	5284569
ChEMBL	CHEMBL1457
IUPHAR	7081
BindingDB	50386689
DrugBank	DB00956
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
190507	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
190508	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
526973	Mas-related G-protein coupled receptor member X2	Q96LB1	MRGPRX2	Homo sapiens (Human)	330
190506	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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