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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3355964
Molecular formula	C28H35Cl2FN4O
IUPAC name	1-[(2R)-1-(3,4-dichlorophenyl)-4-[4-(2-ethyl-6-fluoro-1H-indol-3-yl)piperidin-1-yl]butan-2-yl]-3-ethylurea
Molecular weight	533.513
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	6.7
Synonyms	BDBM50041090
Inchi Key	KVUCRPZZSWTVEJ-NRFANRHFSA-N
Inchi ID	InChI=1S/C28H35Cl2FN4O/c1-3-25-27(22-7-6-20(31)17-26(22)34-25)19-9-12-35(13-10-19)14-11-21(33-28(36)32-4-2)15-18-5-8-23(29)24(30)16-18/h5-8,16-17,19,21,34H,3-4,9-15H2,1-2H3,(H2,32,33,36)/t21-/m0/s1
PubChem CID	118721204
ChEMBL	CHEMBL3355964
IUPHAR	N/A
BindingDB	50041090
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
448757	C-C chemokine receptor type 3	O54814	Ccr3	Rattus norvegicus (Rat)	359
448758	C-C chemokine receptor type 3	P51677	CCR3	Homo sapiens (Human)	355
448756	Probable C-C chemokine receptor type 3	P51678	Ccr3	Mus musculus (Mouse)	359

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