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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	TUG-770
Molecular formula	C19H14FNO2
IUPAC name	3-[4-[2-[2-(cyanomethyl)phenyl]ethynyl]-2-fluorophenyl]propanoic acid
Molecular weight	307.324
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.5
Synonyms	3-(4-{[2-(Cyanomethyl)phenyl]ethynyl}-2-fluorophenyl)propanoic acid BDBM50434295 GTPL6483 W-6124 CS-1524 QC-4555 3-(4-((2-(cyanomethyl)phenyl)ethynyl)-2-fluorophenyl)propanoic acid BC600433 DTXSID90735197 4CA-1291 HY-15697 ZINC95930190 AB0095804 D0S0QY SCHEMBL12983515 3-(4-{2-[2-(cyanomethyl)phenyl]ethynyl}-2-fluorophenyl)propanoic acid BCP07966 FT-0722551 TUG770 CHEMBL2386353 KB-145939 1402601-82-4 AKOS030235391 DA-45349 TUG 770 [ Show all ]
Inchi Key	KIZUBVPJNPVIIN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)
PubChem CID	66553168
ChEMBL	CHEMBL2386353
IUPHAR	6483
BindingDB	50434295
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
170296	Free fatty acid receptor 1	O14842	FFAR1	Homo sapiens (Human)	300
170297	Free fatty acid receptor 1	Q76JU9	Ffar1	Mus musculus (Mouse)	300
170298	Free fatty acid receptor 1	Q8K3T4	Ffar1	Rattus norvegicus (Rat)	300
170295	Free fatty acid receptor 4	Q5NUL3	FFAR4	Homo sapiens (Human)	377

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