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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Arbaclofen placarbil
Molecular formula	C19H26ClNO6
IUPAC name	(3R)-3-(4-chlorophenyl)-4-[[(1S)-2-methyl-1-(2-methylpropanoyloxy)propoxy]carbonylamino]butanoic acid
Molecular weight	399.868
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	4.2
Synonyms	CHEMBL2107312 KB-81511 XP19986 SCHEMBL351833 847353-30-4 Arbaclofen placarbil [USAN:INN] FT-0686949 XP 19986 D08861 R-baclofen - XenoPort ZINC14209416 (3R)-3-(4-Chlorophenyl)-4-((((1S)-2-methyl-1-((2- methylpropanoyl)oxy)propoxy)carbonyl)amino)butanoic acid DB08892 UNII-W89H91R7VX Benzenepropanoic acid, 4-chloro-beta-(((((1S)-2-methyl-1-(2-methyl-1-oxopropoxy)propoxy)carbonyl)amino)methyl)-, (betaR)- JXTAALBWJQJLGN-KSSFIOAISA-N XP-19986 D0GX3L SB17500 (3r)-4-{[(1S)-2-methyl-1-(2-methylpropanoyloxy)propoxy]carbonylamino}-3-(4-chlorophenyl)butanoic acid DTXSID40233754 W89H91R7VX Arbaclofen placarbil (USAN/INN) [ Show all ]
Inchi Key	JXTAALBWJQJLGN-KSSFIOAISA-N
Inchi ID	InChI=1S/C19H26ClNO6/c1-11(2)17(24)26-18(12(3)4)27-19(25)21-10-14(9-16(22)23)13-5-7-15(20)8-6-13/h5-8,11-12,14,18H,9-10H2,1-4H3,(H,21,25)(H,22,23)/t14-,18-/m0/s1
PubChem CID	11281011
ChEMBL	N/A
IUPHAR	N/A
BindingDB	N/A
DrugBank	DB08892
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
549939	Gamma-aminobutyric acid type B receptor subunit 1	Q9UBS5	GABBR1	Homo sapiens (Human)	961
549938	Gamma-aminobutyric acid type B receptor subunit 2	O75899	GABBR2	Homo sapiens (Human)	941

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