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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL420262
Molecular formula	C29H37NO5
IUPAC name	(1S,2S,3S)-2-[1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-nonylcyclopropane-1-carboxylic acid
Molecular weight	479.617
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	4.5
Synonyms	(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-3-nonyl-cyclopropanecarboxylic acid BDBM50072174
Inchi Key	JHMUTZFKEQDSCJ-FBQMFOLFSA-N
Inchi ID	InChI=1S/C29H37NO5/c1-2-3-4-5-6-7-8-15-21-25(27(31)32)26(21)29(30,28(33)34)18-22-19-13-9-11-16-23(19)35-24-17-12-10-14-20(22)24/h9-14,16-17,21-22,25-26H,2-8,15,18,30H2,1H3,(H,31,32)(H,33,34)/t21-,25+,26+,29?/m1/s1
PubChem CID	44329029
ChEMBL	CHEMBL420262
IUPHAR	N/A
BindingDB	50072174
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
151151	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
151153	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
151150	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
151152	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
151154	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
151148	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
151149	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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