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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	NAXAGOLIDE
Molecular formula	C15H21NO2
IUPAC name	(4aR,10bR)-4-propyl-2,3,4a,5,6,10b-hexahydrobenzo[h][1,4]benzoxazin-9-ol
Molecular weight	247.338
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	2.4
Synonyms	BCP9000980 DTXSID60236782 Naxagolida [INN-Spanish] RL05487 1,2,3,4a,5,6-hexahydro-9-hydroxy-4-n-propyl-4H-naphth(1,2-b)(1,4)oxazine 3,4,4A,5,6,10B-hexahydro-4-propyl-2H-naphth(1,2-B)(1,4)oxozin-9-ol AC1L1N70 CHEMBL1288585 l-64739 Naxagolidum ZINC22064446 (+)-PHNO 4-propyl-9-hydroxynaphoxazine API0007626 D0TH1Z N-0500 PHNO (4aR,10bR)-4-propyl-2,3,4a,5,6,10b-hexahydrobenzo[h][1,4]benzoxazin-9-ol BDBM50020217 J-501357 SCHEMBL221758 (+)-4-propyl-9-hydroxynaphoxazine 22Z7E0X6OF 4-Propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol AKOS005146337 LS-178034 Naxagolidum [INN-Latin] [11C]-(+)-(4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol (4ar)-3,4,4a\|A,5,6,10b\|A-hexahydro-4-propyl-2h-naphth[1,2-b]-1,4-oxazin-9-ol 4-propyl-9-hydroxynaphthoxazine BCP02364 dopazinol Naxagolida PHNO,(+) (4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol 88058-88-2 BDBM50331552 JCSREICEMHWFAY-HUUCEWRRSA-N Naxagolide [INN] UNII-22Z7E0X6OF (+)-4-Propyl-9-hydroxynaphthoxazine 2H-Naphth(1,2-b)-1,4-oxazin-9-ol, 3,4,4a,5,6,10b-hexahydro-4-propyl-, (4aR-trans)- 4-Propyl-9-hydroxy-1,2,3,4a,5,6-hexahydronaphthoxazine AN-16576 CHEMBL69271 N 0500 Nazagolide (4ar,10br)-3,4,4a,5,6,10b-hexahydro-4-propyl-2h-naphth(1,2-b)-1,4-oxazin-9-ol [ Show all ]
Inchi Key	JCSREICEMHWFAY-HUUCEWRRSA-N
Inchi ID	InChI=1S/C15H21NO2/c1-2-7-16-8-9-18-15-13-10-12(17)5-3-11(13)4-6-14(15)16/h3,5,10,14-15,17H,2,4,6-9H2,1H3/t14-,15-/m1/s1
PubChem CID	57533
ChEMBL	CHEMBL69271
IUPHAR	N/A
BindingDB	50020217, 50331552
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
147715	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
147716	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
147713	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
147711	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
147714	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
147712	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
556036	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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