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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL319732
Molecular formula	C26H31NO5
IUPAC name	(1S,2S,3S)-2-[1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-hexylcyclopropane-1-carboxylic acid
Molecular weight	437.536
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	2.9
Synonyms	BDBM50072173 (1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-3-hexyl-cyclopropanecarboxylic acid
Inchi Key	HOARSDISRSQYDP-LLQWRFHZSA-N
Inchi ID	InChI=1S/C26H31NO5/c1-2-3-4-5-12-18-22(24(28)29)23(18)26(27,25(30)31)15-19-16-10-6-8-13-20(16)32-21-14-9-7-11-17(19)21/h6-11,13-14,18-19,22-23H,2-5,12,15,27H2,1H3,(H,28,29)(H,30,31)/t18-,22+,23+,26?/m1/s1
PubChem CID	44329031
ChEMBL	CHEMBL319732
IUPHAR	N/A
BindingDB	50072173
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
119809	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
119806	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
119811	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
119807	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
119808	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
119810	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
119805	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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