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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	N-(2-chlorobenzyl)-N'-(2-methylphenyl)-N-(pyridin-3-ylmethyl)thiourea
Molecular formula	C21H20ClN3S
IUPAC name	1-[(2-chlorophenyl)methyl]-3-(2-methylphenyl)-1-(pyridin-3-ylmethyl)thiourea
Molecular weight	381.922
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	4.6
Synonyms	ZINC3662249 HMS2720L22 MolPort-007-585-342 1-[(2-chlorophenyl)methyl]-3-(2-methylphenyl)-1-(pyridin-3-ylmethyl)thiourea SR-01000547719 MCULE-5051311391 AC1N4DO3 SR-01000547719-1 CHEMBL1509954 MLS000729620 SMR000307897 AKOS001775002 [ Show all ]
Inchi Key	HNYLELVFGLFRPB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H20ClN3S/c1-16-7-2-5-11-20(16)24-21(26)25(14-17-8-6-12-23-13-17)15-18-9-3-4-10-19(18)22/h2-13H,14-15H2,1H3,(H,24,26)
PubChem CID	4153842
ChEMBL	CHEMBL1509954
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
119734	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
119735	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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