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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL103388
Molecular formula	C24H31N5O3S
IUPAC name	N-[4-[[5-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-1,1-dioxo-1,2,5-thiadiazolidin-2-yl]methyl]phenyl]acetamide
Molecular weight	469.604
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	1.8
Synonyms	BDBM50422029 SCHEMBL8807080 2-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-5-[4-(acetylamino)benzyl]-1,2,5-thiadiazolidine 1,1-dioxide
Inchi Key	HLROMXIAWNSEJU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H31N5O3S/c1-18(30)26-22-7-4-19(5-8-22)16-28-12-13-29(33(28,31)32)17-20-6-9-24-23(14-20)21(15-25-24)10-11-27(2)3/h4-9,14-15,25H,10-13,16-17H2,1-3H3,(H,26,30)
PubChem CID	10412397
ChEMBL	CHEMBL103388
IUPHAR	N/A
BindingDB	50422029
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
118169	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
118168	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
118170	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357

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