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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2333732
Molecular formula	C20H21ClN4O
IUPAC name	4-[4-[[1-(4-chlorophenyl)pyrazol-4-yl]methyl]piperazin-1-yl]phenol
Molecular weight	368.865
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.6
Synonyms	BDBM50429260
Inchi Key	HBGSAORKQHKGPY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H21ClN4O/c21-17-1-3-19(4-2-17)25-15-16(13-22-25)14-23-9-11-24(12-10-23)18-5-7-20(26)8-6-18/h1-8,13,15,26H,9-12,14H2
PubChem CID	71652196
ChEMBL	CHEMBL2333732
IUPHAR	N/A
BindingDB	50429260
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
110478	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
110473	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
110474	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
110477	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
110475	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
110476	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
110479	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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