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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL14439
Molecular formula	C21H29NO4S
IUPAC name	3-[4-[(2R)-2-[(E)-3-hydroxy-4-phenylbut-1-enyl]-5-oxopyrrolidin-1-yl]butylsulfanyl]propanoic acid
Molecular weight	391.526
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.3
Synonyms	3-[4-[(2R)-2beta-(3-Hydroxy-4-phenyl-1-butenyl)-5-oxopyrrolizino]butylthio]propionic acid BDBM50125398 3-{4-[(R)-2-((E)-3-Hydroxy-4-phenyl-but-1-enyl)-5-oxo-pyrrolidin-1-yl]-butylsulfanyl}-propionic acid
Inchi Key	GYDHQUSXESKSIV-FCRBFTOGSA-N
Inchi ID	InChI=1S/C21H29NO4S/c23-19(16-17-6-2-1-3-7-17)10-8-18-9-11-20(24)22(18)13-4-5-14-27-15-12-21(25)26/h1-3,6-8,10,18-19,23H,4-5,9,11-16H2,(H,25,26)/b10-8+/t18-,19?/m0/s1
PubChem CID	44269520
ChEMBL	CHEMBL14439
IUPHAR	N/A
BindingDB	50125398
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
108160	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
108164	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
108158	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
108159	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
108163	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
108165	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
108161	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359
108162	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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