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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	L-888607
Molecular formula	C19H15ClFNO2S
IUPAC name	2-[(3S)-4-(4-chlorophenyl)sulfanyl-7-fluoro-2,3-dihydro-1H-pyrrolo[1,2-a]indol-3-yl]acetic acid
Molecular weight	375.842
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.4
Synonyms	ZINC6745293 2-[(1S)-9-[(4-chlorophenyl)sulfanyl]-6-fluoro-1H,2H,3H-benzo[b]pyrrolizin-1-yl]acetic acid D0QE3V AJ-56816 L 888607 CHEMBL370606 LMX71OP17X [(S)-9-(4-Chloro-phenylsulfanyl)-6-fluoro-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl]-acetic acid GTPL1907 BDBM50174361 L-888,607 1H-Pyrrolo(1,2-a)indole-1-acetic acid, 9-((4-chlorophenyl)thio)-6-fluoro-2,3-dihydro-, (1S)- CS-0034796 UNII-LMX71OP17X 860033-06-3 HY-111271 [ Show all ]
Inchi Key	GSBAVONRPNJJOH-NSHDSACASA-N
Inchi ID	InChI=1S/C19H15ClFNO2S/c20-12-1-4-14(5-2-12)25-19-15-6-3-13(21)10-16(15)22-8-7-11(18(19)22)9-17(23)24/h1-6,10-11H,7-9H2,(H,23,24)/t11-/m0/s1
PubChem CID	44403763
ChEMBL	CHEMBL370606
IUPHAR	1907
BindingDB	50174361
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
103980	Prostaglandin D2 receptor 2	Q9Y5Y4	PTGDR2	Homo sapiens (Human)	395
553761	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359
103979	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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