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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL102645
Molecular formula	C17H26N4O2S
IUPAC name	2-[5-[(3,3-dimethyl-1,1-dioxo-1,2,5-thiadiazolidin-2-yl)methyl]-1H-indol-3-yl]-N,N-dimethylethanamine
Molecular weight	350.481
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	1.6
Synonyms	BDBM50422018 SCHEMBL8806287 2-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-3,3-dimethyl-1,2,5-thiadiazolidine 1,1-dioxide
Inchi Key	GNNYKNUIVNJLEO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H26N4O2S/c1-17(2)12-19-24(22,23)21(17)11-13-5-6-16-15(9-13)14(10-18-16)7-8-20(3)4/h5-6,9-10,18-19H,7-8,11-12H2,1-4H3
PubChem CID	10383252
ChEMBL	CHEMBL102645
IUPHAR	N/A
BindingDB	50422018
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
100725	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
100724	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
100723	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357

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