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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3287569
Molecular formula	C27H25ClN2O3
IUPAC name	(3S)-3-[4-[[3-(4-chloro-2-methylphenyl)phenyl]methoxy]phenyl]-3-(1-methylimidazol-2-yl)propanoic acid
Molecular weight	460.958
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.3
Synonyms	BDBM50019939 GFFXCPIMXLSUGF-VWLOTQADSA-N (S)-3-[4-(4'-Chloro-2'-methyl-biphenyl-3-ylmethoxy)-phenyl]-3-(1-methyl-1H-imidazol-2-yl)-propionic acid SCHEMBL4676915
Inchi Key	GFFXCPIMXLSUGF-VWLOTQADSA-N
Inchi ID	InChI=1S/C27H25ClN2O3/c1-18-14-22(28)8-11-24(18)21-5-3-4-19(15-21)17-33-23-9-6-20(7-10-23)25(16-26(31)32)27-29-12-13-30(27)2/h3-15,25H,16-17H2,1-2H3,(H,31,32)/t25-/m0/s1
PubChem CID	11961321
ChEMBL	CHEMBL3287569
IUPHAR	N/A
BindingDB	50019939
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
95053	Free fatty acid receptor 1	O14842	FFAR1	Homo sapiens (Human)	300
524255	Free fatty acid receptor 1	Q76JV1	FFAR1	Macaca fascicularis (Crab-eating macaque)	300
524256	Free fatty acid receptor 1	Q8K3T4	Ffar1	Rattus norvegicus (Rat)	300
538345	Melanocortin receptor 4	P70596	Mc4r	Rattus norvegicus (Rat)	332

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