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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Free fatty acid receptor 1
Species	Macaca fascicularis (Crab-eating macaque)
Gene	FFAR1
Synonym	G-protein coupled receptor 40
Disease	N/A for non-human GPCRs
Length	300
Amino acid sequence	MDLPPQLSFALYVAAFALGFPLNVLAIRGARAHARRRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFGVAHFAPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFVLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALAHSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLNPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGSTSQK
UniProt	Q76JV1
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3751659
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3287569
Molecular formula	C27H25ClN2O3
IUPAC name	(3S)-3-[4-[[3-(4-chloro-2-methylphenyl)phenyl]methoxy]phenyl]-3-(1-methylimidazol-2-yl)propanoic acid
Molecular weight	460.958
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.3
Synonyms	BDBM50019939 GFFXCPIMXLSUGF-VWLOTQADSA-N (S)-3-[4-(4'-Chloro-2'-methyl-biphenyl-3-ylmethoxy)-phenyl]-3-(1-methyl-1H-imidazol-2-yl)-propionic acid SCHEMBL4676915
Inchi Key	GFFXCPIMXLSUGF-VWLOTQADSA-N
Inchi ID	InChI=1S/C27H25ClN2O3/c1-18-14-22(28)8-11-24(18)21-5-3-4-19(15-21)17-33-23-9-6-20(7-10-23)25(16-26(31)32)27-29-12-13-30(27)2/h3-15,25H,16-17H2,1-2H3,(H,31,32)/t25-/m0/s1
PubChem CID	11961321
ChEMBL	CHEMBL3287569
IUPHAR	N/A
BindingDB	50019939
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
EC50	29.0 nM	PMID26620255	BindingDB,ChEMBL
Emax	96.0 %	PMID26620255	ChEMBL

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