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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL280442
Molecular formula	C22H31NO4
IUPAC name	7-[(2R)-2-[(E)-3-hydroxy-5-phenylpent-1-enyl]-5-oxopyrrolidin-1-yl]heptanoic acid
Molecular weight	373.493
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.9
Synonyms	7-[(R)-2-((E)-3-Hydroxy-5-phenyl-pent-1-enyl)-5-oxo-pyrrolidin-1-yl]-heptanoic acid BDBM50125413 7-[(2R)-2beta-(3-Hydroxy-5-phenyl-1-pentenyl)-5-oxopyrrolizino]heptanoic acid
Inchi Key	GDVRZKITCJWGMS-KWBANXLOSA-N
Inchi ID	InChI=1S/C22H31NO4/c24-20(14-11-18-8-4-3-5-9-18)15-12-19-13-16-21(25)23(19)17-7-2-1-6-10-22(26)27/h3-5,8-9,12,15,19-20,24H,1-2,6-7,10-11,13-14,16-17H2,(H,26,27)/b15-12+/t19-,20?/m0/s1
PubChem CID	44269596
ChEMBL	CHEMBL280442
IUPHAR	N/A
BindingDB	50125413
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
94025	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
94024	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
94022	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
94027	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
94028	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
94029	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
94023	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359
94026	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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