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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL62529
Molecular formula	C22H23N3
IUPAC name	14-methyl-4,14,24-triazapentacyclo[15.7.0.03,11.05,10.018,23]tetracosa-1(17),3(11),5,7,9,18,20,22-octaene
Molecular weight	329.447
Hydrogen bond acceptor	1
Hydrogen bond donor	2
XlogP	4.5
Synonyms	7-methyl-5,6,7,8,9,14,15,16-octahydroindolo[2'',3'':7,8]azecino[5,4-b]indole BDBM50088344
Inchi Key	FPGUOUPJSRGOEB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H23N3/c1-25-12-10-17-15-6-2-4-8-19(15)23-21(17)14-22-18(11-13-25)16-7-3-5-9-20(16)24-22/h2-9,23-24H,10-14H2,1H3
PubChem CID	10830233
ChEMBL	CHEMBL62529
IUPHAR	N/A
BindingDB	50088344
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
83989	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
445036	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
83990	D(1A) dopamine receptor	Q61616	Drd1	Mus musculus (Mouse)	446
83991	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
83986	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
83987	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
83988	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460

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