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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL329236
Molecular formula	C8H11NO6
IUPAC name	(1S,2S)-4-aminocyclopentane-1,2,4-tricarboxylic acid
Molecular weight	217.177
Hydrogen bond acceptor	7
Hydrogen bond donor	4
XlogP	-4.0
Synonyms	(1S,2S)-4-Amino-cyclopentane-1,2,4-tricarboxylic acid ZINC2575698 (1S,2S)-4-aminocyclopentane-1,2,4-tricarboxylic acid BDBM50060134 (1S)-4-Aminocyclopentane-1alpha,2beta,4beta-tricarboxylic acid SCHEMBL13319984 4-Amino-cyclopentane-1,2,4-tricarboxylic acid(3S,4S-ACPT-III) [ Show all ]
Inchi Key	FERIKTBTNCSGJS-IMJSIDKUSA-N
Inchi ID	InChI=1S/C8H11NO6/c9-8(7(14)15)1-3(5(10)11)4(2-8)6(12)13/h3-4H,1-2,9H2,(H,10,11)(H,12,13)(H,14,15)/t3-,4-/m0/s1
PubChem CID	10656383
ChEMBL	CHEMBL329236
IUPHAR	N/A
BindingDB	50060134
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
76545	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
76547	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
76544	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
76546	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912

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