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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL337101
Molecular formula	C19H19N5S
IUPAC name	7-[4-(thiophen-2-ylmethyl)piperazin-1-yl]-2,8,13-triazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7,10,12-hexaene
Molecular weight	349.456
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.6
Synonyms	6-[4-(2-Thienylmethyl)piperazino]pyrido[3,2-e]pyrrolo[1,2-a]pyrazine BDBM50081976 6-(4-Thiophen-2-ylmethyl-piperazin-1-yl)-pyrido[3,2-e]pyrrolo[1,2-a]pyrazine
Inchi Key	FBZIPLZZCYHKRT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H19N5S/c1-5-16-18(20-7-1)24-8-2-6-17(24)19(21-16)23-11-9-22(10-12-23)14-15-4-3-13-25-15/h1-8,13H,9-12,14H2
PubChem CID	10689158
ChEMBL	CHEMBL337101
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
74718	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
74716	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
74714	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
74717	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
74715	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388

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