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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL222424
Molecular formula	C27H27F2N3O
IUPAC name	1-(1-benzylpiperidin-4-yl)-4,4-bis(4-fluorophenyl)imidazolidin-2-one
Molecular weight	447.53
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.6
Synonyms	BDBM50208001 3-(1-benzyl-piperidin-4-yl)-5,5-di-(4-fluorophenyl)-imidazolidin-2-one
Inchi Key	DLFIQCGXPLUMEB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H27F2N3O/c28-23-10-6-21(7-11-23)27(22-8-12-24(29)13-9-22)19-32(26(33)30-27)25-14-16-31(17-15-25)18-20-4-2-1-3-5-20/h1-13,25H,14-19H2,(H,30,33)
PubChem CID	16125372
ChEMBL	CHEMBL222424
IUPHAR	N/A
BindingDB	50208001
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
62893	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
62891	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
62892	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589

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