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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL183956
Molecular formula	C9H12FNO5
IUPAC name	(1R,2R,3R,5R,6R)-2-amino-6-fluoro-3-methoxybicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Molecular weight	233.195
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	-3.4
Synonyms	SCHEMBL4968500 (1R,2R,3R,5R,6R)-2-amino-6-fluoro-3-methoxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid BDBM50151456
Inchi Key	DLCJNGFLKRARDD-CGFYFEPUSA-N
Inchi ID	InChI=1S/C9H12FNO5/c1-16-4-2-3-5(8(3,10)6(12)13)9(4,11)7(14)15/h3-5H,2,11H2,1H3,(H,12,13)(H,14,15)/t3-,4-,5+,8-,9+/m1/s1
PubChem CID	10192719
ChEMBL	CHEMBL183956
IUPHAR	N/A
BindingDB	50151456
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
62812	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
559210	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
62813	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879

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