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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000778612
Molecular formula	C18H16N2O5S3
IUPAC name	N-[(5Z)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-4-methylbenzenesulfonamide
Molecular weight	436.515
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	3.8
Synonyms	N-[(5Z)-5-[(3-methoxy-4-oxidanyl-phenyl)methylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]-4-methyl-benzenesulfonamide HMS2748G05 N-{5-[1-(4-Hydroxy-3-methoxy-phenyl)-meth-(Z)-ylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-4-methyl-benze nesulfonamide 359898-57-0 N-[(5Z)-4-keto-2-thioxo-5-vanillylidene-thiazolidin-3-yl]-4-methyl-benzenesulfonamide STK995357 AKOS002216749 CHEMBL1392012 N-[(5Z)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-4-methylbenzenesulfonamide SMR000415406 5-[(4-hydroxy-3-methoxyphenyl)methylene]-3-{[(4-methylphenyl)sulfonyl]amino}-2 -thioxo-1,3-thiazolidin-4-one N-[(5Z)-5-(4-hydroxy-3-methoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-4-methylbenzenesulfonamide ZINC2451973 BDBM54096 cid_2047042 N-[(5Z)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]-4-methylbenzenesulfonamide MolPort-000-401-928 ST50158543 AC1M1DRH [ Show all ]
Inchi Key	DJRZIPLCKFJXHA-YBEGLDIGSA-N
Inchi ID	InChI=1S/C18H16N2O5S3/c1-11-3-6-13(7-4-11)28(23,24)19-20-17(22)16(27-18(20)26)10-12-5-8-14(21)15(9-12)25-2/h3-10,19,21H,1-2H3/b16-10-
PubChem CID	2047042
ChEMBL	CHEMBL1392012
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
61772	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
61771	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
470545	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
61770	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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