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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	143069-08-3
Molecular formula	C25H26N4
IUPAC name	N-[4-(4-ethylpiperazin-1-yl)phenyl]acridin-9-amine
Molecular weight	382.511
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.4
Synonyms	CBDivE_005028 N-(4-(4-Ethyl-1-piperazinyl)phenyl)-9-acridinamine 9-Acridinamine,N-[4-(4-ethyl-1-piperazinyl)phenyl]- CTK4C3465 TCMDC-124255 AKOS030561802 GNF-PF-3878 N-(4-(4-ethylpiperazin-1-yl)phenyl)acridin-9-amine AC1MILKO D07ICV BDBM50196122 LS-14146 9-Acridinamine, N-(4-(4-ethyl-1-piperazinyl)phenyl)- CHEMBL217366 N-[4-(4-ethylpiperazin-1-yl)phenyl]acridin-9-amine ACMC-20n23a DTXSID10162300 [ Show all ]
Inchi Key	CUVBGWMAORETGV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H26N4/c1-2-28-15-17-29(18-16-28)20-13-11-19(12-14-20)26-25-21-7-3-5-9-23(21)27-24-10-6-4-8-22(24)25/h3-14H,2,15-18H2,1H3,(H,26,27)
PubChem CID	3072540
ChEMBL	CHEMBL217366
IUPHAR	N/A
BindingDB	50196122
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
51148	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
51149	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
51147	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462

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