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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL466462
Molecular formula	C18H20FN5O2
IUPAC name	(2R)-2-amino-3-[4-(7-fluoropyrrolo[1,2-a]quinoxalin-4-yl)piperazin-1-yl]propanoic acid
Molecular weight	357.389
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	-0.4
Synonyms	BDBM50258495 (R)-2-Amino-3-[4-(7-fluoropyrrolo[1,2-a]quinoxalin-4-yl)piperazin-1-yl]propionic Acid
Inchi Key	CTKOQDQPYZTIFY-CYBMUJFWSA-N
Inchi ID	InChI=1S/C18H20FN5O2/c19-12-3-4-15-14(10-12)21-17(16-2-1-5-24(15)16)23-8-6-22(7-9-23)11-13(20)18(25)26/h1-5,10,13H,6-9,11,20H2,(H,25,26)/t13-/m1/s1
PubChem CID	44157837
ChEMBL	CHEMBL466462
IUPHAR	N/A
BindingDB	50258495
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
50185	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
50183	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
50188	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
50186	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
50187	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
50184	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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