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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL287080
Molecular formula	C24H31F3O5
IUPAC name	(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]pent-1-enyl]cyclopentyl]hept-5-enoic acid
Molecular weight	456.502
Hydrogen bond acceptor	8
Hydrogen bond donor	4
XlogP	3.6
Synonyms	9.alpha.,11.alpha.,15S-Trihydroxy-17-trifluoromethylphenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-oic acid SR-01000946521 17-trifluoromethylphenyl trinor Prostaglandin F2.alpha. J-014533 BDBM50090133 SR-01000946521-1 (Z)-7-[(1R)-2beta-[(1E,3S)-3-Hydroxy-5-[3-(trifluoromethyl)phenyl]-1-pentenyl]-3alpha,5alpha-dihydroxycyclopentane-1alpha-yl]-5-heptenoic acid CMLNDCUXASGBMQ-NQUQXYBYSA-N MolPort-027-640-968 ZINC29322759 (Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-(S)-3-hydroxy-5-(3-trifluoromethyl-phenyl)-pent-1-enyl]-cyclopentyl}-hept-5-enoic acid HMS3648J22 [ Show all ]
Inchi Key	CMLNDCUXASGBMQ-NQUQXYBYSA-N
Inchi ID	InChI=1S/C24H31F3O5/c25-24(26,27)17-7-5-6-16(14-17)10-11-18(28)12-13-20-19(21(29)15-22(20)30)8-3-1-2-4-9-23(31)32/h1,3,5-7,12-14,18-22,28-30H,2,4,8-11,15H2,(H,31,32)/b3-1-,13-12+/t18-,19+,20+,21-,22+/m0/s1
PubChem CID	9825293
ChEMBL	CHEMBL287080
IUPHAR	N/A
BindingDB	50090133
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
45458	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
45460	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
45457	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359
45459	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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