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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000103840
Molecular formula	C20H19F3N4O2
IUPAC name	[5-(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-piperidin-1-ylmethanone
Molecular weight	404.393
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	3.5
Synonyms	[5-(4-methoxyphenyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinyl]-(1-piperidinyl)methanone BDBM48984 MolPort-001-493-659 [5-(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-piperidin-1-ylmethanone 313986-46-8 cid_1244790 SR-01000406567 STK342483 AC1LOQAP MLS000107876 [5-(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](piperidin-1-yl)methanone SCHEMBL1718800 SR-01000406567-1 [5-(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-piperidino-methanone HMS2484P07 ZINC1053013 AKOS003603113 MLS001384952 [5-(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-piperidin-1-yl-methanone CHEMBL1471467 ST000997 5-(4-methoxyphenyl)-7-(trifluoromethyl)(8-hydropyrazolo[1,5-a]pyrimidin-2-yl) piperidyl ketone MCULE-4156587313 [ Show all ]
Inchi Key	CFLAIXWXKXQQEB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H19F3N4O2/c1-29-14-7-5-13(6-8-14)15-11-17(20(21,22)23)27-18(24-15)12-16(25-27)19(28)26-9-3-2-4-10-26/h5-8,11-12H,2-4,9-10H2,1H3
PubChem CID	1244790
ChEMBL	CHEMBL1471467
IUPHAR	N/A
BindingDB	48984
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
40730	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
40729	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
40731	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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