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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL494093
Molecular formula	C17H21N5
IUPAC name	4-(4-methylpiperazin-1-yl)-5,6-dihydrobenzo[h]quinazolin-2-amine
Molecular weight	295.39
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.1
Synonyms	6-(4-methylpiperazin-1-yl)-3,5-diazatricyclo[8.4.0.0^{2,7}]tetradeca-1(14),2,4,6,10,12-hexaen-4-amine 2,4-diamino-5,6-disubstituted pyrimidine, 6 BDBM26392 SCHEMBL4877466
Inchi Key	CEUMRIVIGREJGB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H21N5/c1-21-8-10-22(11-9-21)16-14-7-6-12-4-2-3-5-13(12)15(14)19-17(18)20-16/h2-5H,6-11H2,1H3,(H2,18,19,20)
PubChem CID	25128822
ChEMBL	CHEMBL494093
IUPHAR	N/A
BindingDB	26392
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
522737	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
522738	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
522739	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
40267	Histamine H4 receptor	Q91ZY1	Hrh4	Rattus norvegicus (Rat)	391
40268	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390

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