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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3809630
Molecular formula	C25H31F4N3O4
IUPAC name	5-[2-[2-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenoxy]ethylamino]propyl]-1-(3-hydroxypropyl)-2,3-dihydroindole-7-carboxamide
Molecular weight	513.534
Hydrogen bond acceptor	10
Hydrogen bond donor	3
XlogP	3.7
Synonyms	BDBM50173113
Inchi Key	BRSPJIFNHOLFQU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H31F4N3O4/c1-16(31-6-10-35-21-4-3-19(26)14-22(21)36-15-25(27,28)29)11-17-12-18-5-8-32(7-2-9-33)23(18)20(13-17)24(30)34/h3-4,12-14,16,31,33H,2,5-11,15H2,1H3,(H2,30,34)
PubChem CID	123688273
ChEMBL	CHEMBL3809630
IUPHAR	N/A
BindingDB	50173113
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
522490	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
522492	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
522491	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572

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