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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL566522
Molecular formula	C19H19FN6
IUPAC name	7-fluoro-4-[4-(1H-imidazol-5-ylmethyl)piperazin-1-yl]pyrrolo[1,2-a]quinoxaline
Molecular weight	350.401
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.9
Synonyms	BDBM50299660 7-fluoro-4-(4-((3H-imidazol-4-yl)methyl)piperazin-1-yl)-pyrrolo[1,2-a]quinoxaline
Inchi Key	BRNJLENJYHXKEL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H19FN6/c20-14-3-4-17-16(10-14)23-19(18-2-1-5-26(17)18)25-8-6-24(7-9-25)12-15-11-21-13-22-15/h1-5,10-11,13H,6-9,12H2,(H,21,22)
PubChem CID	44541937
ChEMBL	CHEMBL566522
IUPHAR	N/A
BindingDB	50299660
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
31145	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
31149	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
31147	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
31148	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
31144	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
31146	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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