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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL257606
Molecular formula	C20H32N6
IUPAC name	2-[1-[2-(2-methylpyrrolidin-1-yl)ethyl]-3-(2-piperidin-1-ylethyl)imidazolidin-2-ylidene]propanedinitrile
Molecular weight	356.518
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	2.2
Synonyms	(+/-)-2-(1-(2-(2-methylpyrrolidin-1-yl)ethyl)-3-(2-(piperidin-1-yl)ethyl)imidazolidin-2-ylidene)malononitrile BDBM50237874
Inchi Key	BQWBRQKHFWLAJX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H32N6/c1-18-6-5-9-24(18)12-13-26-15-14-25(20(26)19(16-21)17-22)11-10-23-7-3-2-4-8-23/h18H,2-15H2,1H3
PubChem CID	44447985
ChEMBL	CHEMBL257606
IUPHAR	N/A
BindingDB	50237874
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
30720	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
30719	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
30717	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445
30718	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
30716	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390

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