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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL116153
Molecular formula	C25H28F2N6
IUPAC name	3-[3-[4-[2-(3,5-difluorophenyl)ethyl]piperazin-1-yl]propyl]-5-(1,2,4-triazol-4-yl)-1H-indole
Molecular weight	450.538
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.8
Synonyms	3-(3-{4-[2-(3,5-Difluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole BDBM50060439 L016155 3-[3-[4-(3,5-Difluorophenethyl)piperazino]propyl]-5-(4H-1,2,4-triazol-4-yl)-1H-indole SCHEMBL7474326
Inchi Key	BLVVWPOJELUFFG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H28F2N6/c26-21-12-19(13-22(27)14-21)5-7-32-10-8-31(9-11-32)6-1-2-20-16-28-25-4-3-23(15-24(20)25)33-17-29-30-18-33/h3-4,12-18,28H,1-2,5-11H2
PubChem CID	10503731
ChEMBL	CHEMBL116153
IUPHAR	N/A
BindingDB	50060439
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
27032	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
27031	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377

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